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NNP-BC Exam Format | NNP-BC Course Contents | NNP-BC Course Outline | NNP-BC Exam Syllabus | NNP-BC Exam Objectives

Exam Code: NNP-BC

Exam Name: NCC Neonatal Nurse Practitioner

Exam Type: Computer-based, multiple-choice questions.

Number of Questions: 175 questions (150 scored, 25 unscored pretest questions).

Time Allotted: 3 hours (180 minutes).

Passing Score: Scaled score of 700 (on a scale of 300–900).



- Maternal History affecting the Newborn Antepartum

- Neonatal complications: maternal risk factors & complications

- gestational hypertension

- cardiac/pulmonary disease

- diabetes

- common infectious diseases

- common hematologic diseases

- placental insufficiency

- substance abuse

- medication effects

- Fetal exam

- fetal fibronectin

- nonstress test

- biophysical profile

- ultrasound/doppler flow

- amniocentesis

- antenatal screening/quad screen

- Fetal procedures

- Intrapartum

- Fetal Heart Rate (FHR) Patterns

- Effects on the Fetus/Neonate

- tocolysis/induction

- analgesia

- anesthesia

- neuroprotective agents

- Intrapartum Complications

- amniotic fluid volume

- oligohydramnios

- polyhydramnios

- Rupture of Membranes

- premature

- prolonged

- Intrauterine Drug Exposure

- Nicotine

- Alcohol

- Prescription/nonprescription

- Illicit Drug



- Neonatal

- General appearance

- Head, eyes, nose, ears and mouth

- Neck and throat

- Chest

- Abdomen

- Spine/back

- Extremities

- Genitalia

- Musculoskeletal

- Skin

- Vital signs

- Gestational age exam physical Characteristics of

- preterm

- term

- post-term

- AGA

- SGA

- LGA



- Associated risks/Complications of variations in gestational age

- Abnormalities of intrauterine parameters

- Behavioral exam

- state

- Muscle movement/tone/reflexes

- Autonomic control/responses

- Neurosensory capabilities

- Neurological exam

- Clinical Laboratory Tests

- Microbiological

- Biochemical

- Hematological

- Endocrine

- Immunologic

- Genetic



- Diagnostic studies

- Ultrasound/Doppler

- CT scan

- MRI

- X-ray/fluoroscopy

- EKG

- EEG

- Echocardiogram

- Voiding Cystourethrogram



- Techniques & Equipment

- Procedures

- bag and mask ventilation and T-piece

- LMAs

- endotracheal intubation

- umbilical vessel and peripheral catheterization

- chest tube insertion/removal

- needle aspiration

- spinal/lumbar tap

- intraosseous access

- intravenous line placement (central/peripheral)

- blood sampling

- circumcisions - complications/contraindications



- Equipment

- cardiopulmonary monitors

- oxygenation equipment/end tidal CO2 monitoring

- invasive/non-invasive blood gas monitoring

- indwelling catheters

- incubators/radiant warmers

- ventilators

- phototherapy

- NIRS



- Family Integration

- Communication

- Family centered care

- Barriers to parent/infant interaction

- Grieving Process

- Stages of grieving and common behaviors

- Factors influencing enhancement or impediment of grief process

- Palliative care/End of life

- Parental depression

- Periviability

- Diversity, Equity and Inclusion

• Culturally supportive care



- Discharge Planning and Follow Up

- Anticipatory guidance

- Follow up screening

- Hearing

- Vision - ROP

- Developmental

- Health risks

- Discharge preparation

- Follow-up care



- Thermoregulation

- Mechanisms and management of heat transfer

- evaporation

- conduction

- convection

- radiation

- Rewarming techniques

- Mechanisms of heat production

- Temperature exam

- Neutral thermal environment



- Resuscitation and Stabilization

- Transition to extrauterine life

- Delivery room exam

- Techniques of resuscitation

- Indications for interventions

- Cord blood gas interpretation

- Neonatal transport



- Growth and Nutrition

- Physiology of Digestion and Absorption

- Nutritional Requirements

- Enteral Feeding

- Parenteral Nutrition

- Composition of Breast Milk/Formulas/Donor milk

- Dietary Supplementation



- Fluids and Electrolytes

- Common problems and conditions

- Fluid & Electrolyte requirements

- Insensible water loss/gain

- Central & peripheral infusion

- Acid base balance

- Fish oil emulsion (Omegaven) SMOF



- Pharmacokinetics & Pharmacodynamics

- Pharmacokinetics

- distribution

- excretion

- absorption

- metabolism

- withdrawal

- Principles of administration

- dosage/interval

- route

- tolerance/weaning

- Common Drug Therapies

- Analgesia/narcotics

- Anticoagulants

- Anticonvulsants

- Antihypertensive drugs

- Antimicrobials

- biologics/immunities

- vaccinations

- Cardiovascular drugs

- vasodilators/vasopressors

- antidysrhythmia drugs

- Diuretics

- GI drugs

- antacids

- prokinetic

- proton pump inhibitors

- Inhalants

- iNO

- Neurologic agents

- anesthetics agents

- sedatives

- hypnotics

- Respiratory drugs

- bronchodilators

- respiratory stimulants

- surfactant therapy

- Steroids

- Drugs and breastfeeding

- Drug transfer

- Drug safety



- Cardiac

- Congenital Cardiac Defects

- cyanotic

- Ebsteins Anomaly

- Tetralogy of Fallot

- truncus arteriosus

- transposition of great vessels

- total anomalous pulmonary venous return

- tricuspid atresia

- acyanotic

- ventricular septal defect

- coarctation of aorta (interrupted arch)

- atrial septal defect septal defect

- hypoplastic left heart syndrome

- endocardial cushion defect (AV canal)

- aortic stenosis

- Patent ductus arteriosus

- Congestive heart failure

- Hypertension/Hypotension

- Shock

- Dysrhythmias

- PGEs



- Respiratory

- Respiratory distress syndrome

- Transient tachypnea

- Pneumothorax and air leaks/chylothorax

- Congenital pulmonary airway malformation (CPAM)

- Cystic pulmonary

- Apnea of prematurity

- Meconium aspiration

- Diaphragmatic eventrations

- Persistent pulmonary hypertension

- Pneumonia

- Pulmonary hemorrhage

- Pulmonary hypoplasia

- Diaphragmatic hernia

- Chronic lung disease

- Laryngeal, tracheomalacia/stenosis

- Respiratory support

- principles and methods of oxygen

- administration/ventilation

- risk factors affecting oxygenation/ventilation

- oxyhemoglobin dissociation curve

- high frequency ventilation (HFV)

- extracorporeal membrane oxygenation (ECMO)

- nitric oxide

- neurally adjusted ventilatory assist (NAVA)

- nasal intermittent positive pressure ventilation (NIPPV)

- noninvasive ventilation (NIV)



- Gastrointestinal

- Development of the GI tract

- Digestive and absorptive disorders

- diarrhea/short gut

- Disorders of suck/swallow/motility

- GERD

- cleft lip palate

- Duodenal atresia

- tracheoesophageal fistula -esophageal atresia

- small left colon syndrome

- Hirschsprung disease

- volvulus

- imperforate anus

- pyloric stenosis

- Malabsorption/maldigestion

- Diarrhea/short gut

- Anomalies/obstruction of upper and lower GI tract

- small left colon syndrome

- Hirschsprungs disease

- Abdominal wall defects

- gastroschisis -omphalocele

- Obstructions

- Perforations

- Meconium ileus

- Tracheoesophageal fistula

- Necrotizing enterocolitis

- Inguinal hernia

- Malrotaton



- Renal/Genitourinary

- Renal vein/artery thrombosis

- Acute renal failure/insufficiency

- Polycystic/multicystic dysplastic kidneys

- Urinary outflow tract obstruction

- Testicular torsion

- Exstrophy of the bladder

- Hypospadias/epispadias

- Hydronephrosis grading system/hydroureter



- Endocrine/Metabolic

- Adrenal disorders

- Ambiguous genitalia

- Calcium disorders

- Glucose disorders

- Magnesium disorders

- Phosphorus disorders

- Pituitary disorders

- Thyroid disorders

- Infants of diabetic mothers

- Osteopenia of prematurity



- Hematopoietic

- Hematological disorders

- anemia

- polycythemia

- platelet disorders

- coagulopathies

- vitamin K deficiency

- disseminated intravascular coagulation

- factor deficiencies

- neutropenia/neutrophilia

- Rh disease and ABO incompatibility

- Blood component therapy

- Jaundice and liver disease

- Hyperbilirubinemia (direct and indirect)

- Breastmilk jaundice

- Kernicterus

- Phototherapy

- Exchange transfusion

- Biliary atresia



- Infectious Diseases

- Normal immunologic function

- Common neonatal infections

- group B streptococcal

- e-coli

- staphylococcal

- klebsiella

- enterococcus

- candidiasis

- pseudomonas

- enterovirus

- respiratory syncytial virus (RSV)

- CMV

- hepatitis B

- toxoplasmosis

- herpes

- HIV/AIDS

- chlamydia

- gonorrhea

- syphilis

- varicella

- Neonatal sepsis

- SIRS

- Meningitis

- Septic shock

- Infection control and universal precautions

- MRSA/VRSE

- Osteomyelitis



- Musculoskeletal

- Abnormalities of the skeleton

- metatarsus adductus

- achondroplasia

- Clubfoot

- Developmental dysplasia of the hip

- Spinal abnormalities

- Musculoskeletal birth injuries

- fractures

- nerve damage

- torticollis

- Aperts, crouzon, etc.



- Integumentary

- General skin development and care

- Disorders

- ecchymosis -epidermolysis bullosa

- hemangiomas

- ichthyosis

- subcutaneous fat necrosis

- Milia/miliara

- Hyperpigmented macule

- Erythema toxicum

- Neonatal pustular melanosis

- Auricular tags

- Petechiae

- Port wine stain

- Hyper/hypopigmentation



- Genetics

- Genetic processes

- multifactorial inheritance

- nondisjunction

- translocation

- deletion/duplication

- sex linked inheritance

- Inborn errors of metabolism

- Hyperammonemia

- Newborn Screening

- galactosemia

- cystic fibrosis

- Chromosomal abnormalities/syndromes

- Trisomy 21

- Trisomy 13

- Trisomy 18

- Turner syndrome

- Beckwith-Wiedemann syndrome

- DiGeorge syndrome

- Osteogenesis imperfecta

- Potter sequence

- VATER/VACTERL

- CHARGE



- Neurological

- Perinatal – depression/asphyxia

- Hypoxic ischemic encephalopathy

- therapeutic hypothermia

- Cranial hemorrhages

- Hydrocephalus

- Neural tube defects

- Seizures

- Jitteriness

- Periventricular leukomalacia

- Auto regulation

- Cerebral palsy

- aEEG

- Near-infrared spectroscopy (NIRS)

- Congenital neuromuscular disorders

- Craniosynostosis

- Neurodevelopmental care



- Ears, Eyes, Nose and Throat

- Eyes

- eye prophylaxis

- cataracts

- coloboma

- glaucoma

- retinopathy of prematurity

- strabismus

- conjunctivitis

- Nose

- nasolacrimal duct obstruction

- choanal atresia

- deviated septum

- Ears

- malformations

- Mouth/throat

- cleft lip and palate

- micrognathia/retrognathia

- macroglossia

- airway obstruction

- Ethical Principles

- Autonomy

- Beneficence

- Non-maleficence

- Justice

- Professional/Legal Issues

- Professional

- Regulation

- Practice

- HIPPA

- Staffing issues

- Legal liability

- Consent

- Documentation/medical records

- Negligence/malpractice

- Evidence-based practice

- Terminology

- Reliability

- Validity

- Significance

- Levels of Evidence

- Quality Improvement

- Research utilization

- Neonatal Safety

- Communication

- Interprofessional practice

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