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Latest 2025 Updated ONCC Oncology Certified Nurse - 2025 Questions and Answers

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Exam Number : OCN
Exam Name : ONCC Oncology Certified Nurse - 2025
Vendor Name : Nursing
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Question Bank : Check Questions

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OCN Exam Format | OCN Course Contents | OCN Course Outline | OCN Exam Syllabus | OCN Exam Objectives


Exam ID : OCN


Exam Title : Oncology Certified Nurse (OCN®)


Questions : 165


Duration : 3 hours


Exam Type : multiple-choice





Test Content Outline (Effective 2020)


I. Care Continuum - 19%


A. Health promotion and disease prevention (e.g., high-risk behaviors; preventive health practices)


B. Screening and early detection


C. Navigation


D. Advance care planning (e.g., advance directives)


E. Epidemiology


1. Modifiable risk factors (e.g., smoking, diet, exercise, occupation)


2. Non-modifiable risk factors (e.g., age, gender, genetics)


F. Survivorship


1. Rehabilitation


2. Recurrence concerns


3. Financial concerns


4. Employment concerns


5. Insurance concerns


6. Family and social support concerns


7. Sexuality concerns


G. Treatment-related considerations


1. Delayed-onset side effects


2. Chronic side effects


3. Secondary malignancies


4. Follow-up care


H. End-of-life care


1. Grief


2. Bereavement


3. Hospice care


4. Caregiver support


5. Interdisciplinary team


6. Pharmacologic comfort measures


7. Non-pharmacologic comfort measures


II. Oncology Nursing Practice - 17 %


A. Scientific basis


1. Carcinogenesis


2. Immunology


3. Clinical trials (e.g., research protocols)


B. Site-specific cancer considerations


1. Pathophysiology


2. Common metastatic locations


3. Diagnostic measures


4. Prognosis


5. Classification


6. Staging


7. Histological grading


C. Scope, standards, and related issues


1. Standards of care (nursing process)


2. Legal (including documentation)


3. Accreditation (e.g., The Joint Commission)


4. Self-care (e.g., managing compassion fatigue)


D. Standards of professional performance


1. Ethics (e.g., patient advocacy)


2. Education


3. Evidence-based practice (e.g., Putting Evidence Into Practice (PEP) guidelines) and research


4. Quality of practice


5. Communication


6. Leadership


7. Collaboration


8. Professional practice evaluation


9. Resource utilization


10. Environmental health (e.g., safety, personal protective equipment, safe handling)


III. Treatment Modalities - 19%


A. Surgery


B. Blood and marrow transplant


C. Radiation therapy


D. Chemotherapy


E. Biotherapy


F. Immunotherapy


G. Vascular Access Devices (VADs) for treatment administration


H. Targeted Therapy


IV. Symptom Management and Palliative Care - 23%


A. Etiology and patterns of symptoms (acute, chronic, late)


B. Anatomical and surgical alterations (e.g., lymphedema, ostomy, site-specific radiation)


C. Pharmacologic interventions


D. Complementary and integrative modalities (e.g., massage, acupuncture, herbal supplements)


E. Palliative care considerations


F. Alterations in functioning


1. Hematologic


2. Immune system


3. Gastrointestinal


4. Genitourinary


5. Integumentary


6. Respiratory


7. Cardiovascular


8. Neurological


9. Musculoskeletal


10. Nutrition


11. Cognition


12. Energy level (i.e., fatigue)


V. Oncologic Emergencies - 12%


A. Disseminated intravascular coagulation (DIC)


B. Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)


C. Sepsis (including septic shock)


D. Tumor lysis syndrome


E. Hypersensitivity


F. Anaphylaxis


G. Hypercalcemia


H. Cardiac tamponade


I. Spinal cord compression


J. Superior vena cava syndrome


K. Increased intracranial pressure


L. Obstructions (bowel and urinary)


M. Pneumonitis


N. Extravasations


VI. Psychosocial Dimensions of Care - 10%


A. Cultural, spiritual, and religious diversity


B. Financial concerns (including available resources)


C. Altered body image


D. Learning styles and barriers to learning


E. Social relationships and family dynamics


F. Coping mechanisms and skills


G. Support


1. Patient (i.e., individual and group)


2. Caregiver (including family)


H. Psychosocial considerations


1. Anxiety


2. Loss and grief


3. Depression


4. Loss of personal control


I. Sexuality


1. Reproductive issues (e.g., contraception, fertility)


2. Sexual dysfunction (e.g., physical and psychological effects)


3. Intimacy



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Oncology nursing is a highly specialized field that demands a deep understanding of the complex and multifaceted world of cancer care. Oncology nurses play a vital role in caring for patients with cancer, providing support, administering treatments, managing symptoms, and educating patients and families. To validate their knowledge and expertise, many oncology nurses choose to pursue the OCN (Oncology Certified Nurse) certification exam, offered by the Oncology Nursing Certification Corporation (ONCC).


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The OCN exam is a rigorous and comprehensive assessment that evaluates a nurse's competency in oncology nursing practice. It covers a wide range of topics, including cancer biology, treatment modalities, symptom management, psychosocial aspects of care, and end-of-life care. The exam is designed to test not only the nurse's knowledge but also their critical thinking, clinical judgment, and decision-making skills. Nurses who aspire to become OCN certified must demonstrate a high level of proficiency in these areas, reflecting their commitment to providing safe, evidence-based, and compassionate care to patients with cancer.

Preparing for the OCN exam is a significant undertaking that requires dedicated effort and commitment. Many nurses invest considerable time and resources in exam preparation, which may include completing specialized oncology courses, attending conferences, participating in study groups, and reviewing extensive study materials. The process of preparing for the OCN exam can be challenging but also rewarding, as it allows nurses to deepen their knowledge and expertise in oncology nursing practice.

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Achieving OCN certification is a significant accomplishment that opens doors to numerous career opportunities. OCN-certified nurses are recognized as experts in the field of oncology nursing and are highly sought after by employers who value their advanced knowledge and skills. OCN certification can lead to career advancement, including leadership roles, research opportunities, and academic positions. It also provides a sense of professional accomplishment and personal satisfaction, knowing that the nurse has achieved a high level of expertise in oncology nursing practice.

In conclusion, the OCN Oncology Certified Nurse exam is a challenging and prestigious certification that validates the knowledge and expertise of oncology nurses. It is a mark of distinction in the field of oncology nursing, demonstrating a nurse's commitment to excellence and dedication to providing the highest standard of care to patients with cancer. The process of preparing for the OCN exam is rigorous but rewarding, allowing nurses to deepen their knowledge and enhance their skills in oncology nursing practice. Achieving OCN certification can open doors to new career opportunities and provide a sense of professional accomplishment, making it a valuable credential for oncology nurses who seek to unlock their expertise in cancer care.


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